UK Diagnostic AF Atlas

Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE) is an area of enlarged pigment epithelial cells that contain increased pigment. Clinically, they appear as flat, round pigmented lesions, occasionally with depigmented zones, or as small grouped patches known as bear tracks.

CHRPE

CHRPE

CHRPE appears dark (hypoautofluorescence) on opto map af  image because photoreceptors are absent in this area. RPE cells lose source of lipofuscin and thus it appears dark.

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af Diagnostic Atlas

A Retinal Reference Guide